The Wittig Reaction
Mastering Olefin Synthesis from Mechanism to Application
What if the key to mastering one of organic chemistry's most powerful carbon-carbon bond-forming reactions lies not just in memorizing conditions, but in truly understanding its elegant mechanism? The Wittig reaction has been a cornerstone of synthetic chemistry for decades, yet many practitioners struggle to predict outcomes, optimize conditions, or troubleshoot unexpected results. This book bridges the gap between textbook theory and laboratory reality, providing you with a comprehensive understanding of Wittig olefination that goes beyond surface-level knowledge. You'll explore the mechanistic intricacies that govern stereoselectivity, discover how to choose between classical Wittig and modern modifications, and learn to apply these transformations strategically in complex synthesis. Through detailed analysis of reaction pathways, practical guidance on experimental execution, and real-world examples from natural product synthesis, you'll develop the confidence to deploy Wittig chemistry effectively in your own work. Whether you're planning a multi-step synthesis or optimizing a key transformation, this book equips you with the knowledge to make informed decisions and achieve your synthetic goals.
Est. Length
207 pages (11 chapters)
Language
English
Publication date
Oct 24, 2025
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